It is saying a small number of IBS individuals that do not test positive for celiac disease show some self-reported improvement when place on a gluten free diet. No mechanism for the gluten intolerance in these non-celiac individuals is known. Also, they say that there is a confounding factor. Wheat which is high in gluten is also high in fructans which are known to cause GI symptoms. Also, they say "Wheat proteins are commonly implicated in food hypersensitivity and it must be considered that the induction of symptoms by gluten in this study might be a wheat-specific phenomenon, and not gluten specific."
In summary, the study was small but suggested a small number of IBS individuals may see an improvement in symptoms on a gluten free diet even though they don't have celiac disease. However, they have not been able to exclude the possibility that wheat alone not the gluten in it may be the culprit for some. Also, unlike celiac disease there is no evidence for intestinal inflammation or other organic damage.
-------------------- STABLE: ♂, IBS-D 50+ years - Science of IBS
Posts
Re: the problem is, I don't understand this particular study
