Well, I hope they're able to figure something out in my lifetime! It seems to me progress is being made. I haven't had this long (9 months) but from my reading the probiotic craze is only a couple of years old and that has helped a lot of people. The webpages about IBS all note a whole lot of things have been learned in the past 10 years or so. I intend to donate money to organizations and researchers looking for a cure. There are so many of us, if everyone chipped in $100, well, money talks, y'know?