If you dissolve VSL#3 in a hot liquid it will kill the probiotic bacteria. However, once you drink a cool liquid with the probiotic mixed in it and then if you drink a hot liquid afterwords the hot liquid will be cooled immediately by the stomach juices and therefore the probiotic will not be affected. The reason for the keeping the probiotic in the refrigerator is to prolong the life time of the probiotic bacteria. Some probiotics don't need to be refrigerated because they have been freeze-dried and the probiotic is reactivate once a liquid is added. The method that is used depends on the type of probiotic and the manufacturer's preference.
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Re: VSL#3 - how long to wait before consuming hot food/drinks?
