The night I used the suppository my body finally moved the 4 days of impacted stool (no TMI warning necessary on this site, right? ) and then the next day I had a normal BM. I thought it was a painful-ish experience --only the second time I've ever used one-- but nothing like I've heard senna can be. Some burning and then a little cramping and INSANE (I'm talking HUGE) bloating as everything moved through. Anyway, I want these options to be last-resort only. Maybe I'll give Milk of Magnesia a try.