I take dicyclomine when I absolutely need to but I try to avoid it if I can help it because it makes me so disoriented. I also had my doctor cut my dosage from 20mg to 10mg so that if I have an attack at work I can take one pill and still function. (20mg really puts me flat out and I shouldn't be driving or anything when I take 20mg.) Anyway, the way I look at dicyclomine is that it's great to have for attacks, but it's not good to be on it all the time because it's mainly just treating the attacks, as opposed to coming up with a diet/stress/sleep plan that avoids attacks all together. As far as dicyclomine and anxiety I would say yes it calms me down a little in that I can actually sit still but I also try to avoid taking it late at night because it makes it hard for me to sleep. Anyway, just a little of my experiences with it.